Chemistry: molecular biology and microbiology – Apparatus
Reexamination Certificate
2011-05-24
2011-05-24
DeJong, Eric S (Department: 1631)
Chemistry: molecular biology and microbiology
Apparatus
C435S006120, C702S019000, C702S022000
Reexamination Certificate
active
07947486
ABSTRACT:
A method for analyzing nucleic acid obtained from a cell sample on a platform is described. A platform having a cell selector, a nucleic acid selector, and an array of microlocations, wherein at least one microlocation has an associated capture sequence, is provided. The cell selector is contacted with a cell sample, wherein a portion of the cells remain associated with the cell selector. At least a portion of cells associated with the cell selector are lysed to release a nucleic acid sample. The nucleic acid selector is then contacted with the nucleic acid sample, such that a portion of the nucleic acid sample remains associated with the nucleic acid selector. The associated nucleic acid sample is then released from the nucleic acid selector and then is contacted with the array of microlocations, such that at least a portion of the released nucleic acid sample hybridizes with the capture sequence.
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Evans Glen A.
Heller Michael J.
Sosnowski Ronald G.
Tu Eugene
Cooper & Dunham LLP
Dejong Eric S
Gamida for Life B.V.
White John P.
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