Selenium-75 steroids

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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26023955A, 26023955R, 2603972, 2603973, 26039745, 424 2, C07J 100, G01T 100, C07J 500, C07J 900

Patent

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039520307

ABSTRACT:
Novel dimeric and monomeric selenium-75 derivatives of steroids are made by reacting a keto steroid with selenium-75 dioxide or selenious acid-Se75. The resulting diselenide dimers can be converted into monomeric compounds by the use of a cleaving reagent followed by an alkylating agent. The compounds are useful in saturation analyses such as radioimmunoassays.

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