Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-02-06
2007-02-06
Dentz, Bernard (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C548S183000, C548S217000, C548S465000, C549S058000, C549S468000, C549S471000
Reexamination Certificate
active
10490805
ABSTRACT:
The present invention includes novel retinoid compounds that have selectivity as RXR agonists on one or more isoforms of RXR, currently, RXRα, RXRβ, or RXRγ. The present compounds, and pharmaceutical compositions incorporating these compounds, therefore, are effective in treating conditions mediated by RXRs. Among other physiological responses, the compounds of the present invention reduce blood glucose and maintain body weight, and, thus, are useful for the treatment of diabetes (NIDDIM) and obesity.
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Database Crossfire Beilstein Online! Beilstein Institut zur Forderung der Chemischen Wissenschaften, Franfurt am Main, DE; I. Elghamry: Database accession No. 9073747 XP002235173 abstract & Synth. Commun., vol. 32, No. 6, 2002, pp. 897-902.
Haffner Curt Dale
Kaldor Istvan
McDougald Darryl Lynn
Miller Aaron Bayne
Dentz Bernard
Fix Amy H.
SmithKline Beecham Corporation
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