Selective neuromodulation using energy-efficient waveforms

Details Selective neuromodulation using energy-efficient waveforms Selective neuromodulation using energy-efficient waveforms

2009-06-05

2011-10-25

Manuel, George (Department: 3762)

Surgery: light, thermal, and electrical application

Light, thermal, and electrical application

Electrical therapeutic systems

Reexamination Certificate

active

08046077

ABSTRACT:
Methods of selective neuromodulation in a live mammalian subject, such as a human patient. The method comprises applying an electrical signal to a target site in the nervous system, such as the brain, where the electrical signal comprises a series of pulses. The pulses includes a waveform shape that is more energy-efficient as compared to a corresponding rectangular waveform. Non-limiting examples of such energy-efficient waveforms include linear increasing, linear decreasing, exponential increasing, exponential decreasing, and Gaussian waveforms. The parameters for the energy-efficient waveform are chosen to selectively activate neural tissue on the basis of axonal diameter.

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