Selective inhibitors of rock protein kinase and uses thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S318000, C514S336000, C514S253010, C544S124000, C544S360000, C546S194000, C546S281400

Reexamination Certificate

active

08058271

ABSTRACT:
Described herein are compounds that are useful as ROCK inhibitors. These compounds, and pharmaceutically acceptable compositions thereof, are useful for treating or lessening the severity of a variety of disorders, including cardiovascular, inflammatory, neurological, or proliferative diseases or disorders.

REFERENCES:
patent: 03/062215 (2003-07-01), None
patent: 2004/041813 (2004-05-01), None
patent: 2005/074642 (2005-08-01), None
patent: 2005/100342 (2005-10-01), None
Dorwald , Side Reactions in Organic Synthesis, 2005, Wiley: VCH Weinheim Preface, pp. 1-15 & Chapter 8, pp. 279-308.

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