Selective inhibition of DNA polymerase

Details Selective inhibition of DNA polymerase Selective inhibition of DNA polymerase

1989-04-03

1992-06-09

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 74, 435236, 435184, C12Q 170

Patent

active

051206390

ABSTRACT:
Two peptides, P6 and P7, having the amino acid sequence APGDEPAPPY and AGATAEETRY have been used to obtain antibodies made against them, which antibodies specifically neutralize HSV-1 and HSV-2 DNA polymerase. The present invention also contemplates a method of screening for inhibitors of HSV-1 and HSV-2 polymerase utilizing the antibodies.

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