Selective incorporation of a polymer into implantable biological

Bleaching and dyeing; fluid treatment and chemical modification – Treatment of hides – skins – feathers and animal tissues – Internal tissues

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8 9421, 623 2, A61L 1700, A63B 5102, D01Q 300, D01F 500

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047291397

ABSTRACT:
A process for selectively incorporating biocompatible polymers in the interstices of implantable biological tissue while leaving the outer surface of the tissue substantially free of bonded polymer. The process involves covalently binding a monomer to the tissue, contacting the tissue with a free-radical initiator, then contacting the tissue with a solution containing a second monomer and a free-radical scavenger, thereby promoting selective polymerization of the second monomer with the portion of covalently-bound first monomer which is located in the interstices of the tissue.

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