Selective expansion of target cell populations

Details Selective expansion of target cell populations Selective expansion of target cell populations

1997-10-06

1999-07-20

Saunders, David

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Primate cell, per se

435 2, 435374, 435377, 435395, 435402, 435403, C12N 502, C12N 508

Patent

active

059255676

ABSTRACT:
A method is provided for selective expansion of a predetermined target population of cells, including (a) introducing a starting sample of cells into a growth medium; (b) causing cells of the predetermined target cell population to divide; and (c) concurrently with, intermittently during, or following step (b) contacting the starting cells with a selection element, comprising a plurality of selective binding molecules with specific affinity either for target cells or for non-target cells to select cells of said predetermined target population from other cells in the growth medium. Systems are provided for selective expansion and methods of treating patients with cell populations and products.

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