Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...
Reexamination Certificate
2007-10-30
2007-10-30
Naff, David M. (Department: 1657)
Chemistry: molecular biology and microbiology
Carrier-bound or immobilized enzyme or microbial cell;...
Enzyme or microbial cell is immobilized on or in an organic...
C435S180000, C530S812000, C530S815000
Reexamination Certificate
active
10668679
ABSTRACT:
A method of patterning materials, such as proteins, on a contoured surface by depositing them onto protrusions on a surface, and a cell containment device that may be constructed by this method, are provided. The method may involve selectively depositing a material on a substrate including a contoured surface including protrusions and recesses. By applying a first fluid to the contoured surface and allowing the first fluid to distribute across only a portion of the contoured surface, a material may be deposited on the protrusions and not the recesses, or on the recesses and not the protrusions. Such a method may be used to selectively pattern cells or other materials on substrates.
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Chen Christopher S.
Ingber Donald E.
Ostuni Emanuele
Whitesides George M.
Children's Medical Center Corporation
Naff David M.
President & Fellows of Harvard College
Wolf Greenfield & Sacks P.C.
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