Selective brain stimulation using conditioning pulses

Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems

Reexamination Certificate

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Reexamination Certificate

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06850802

ABSTRACT:
Methods of electrically stimulating neural tissue of the brain are disclosed. A first electrode is placed in close proximity with tissue of a patient's brain (e.g., in the brain, or on or near the surface of the brain). A hyperpolariziag electrical pre-pulse is applied to the tissue through the first electrode wherein the tissue is more susceptible to subsequent electric stimulation. A subsequent depolarizing electrical pulse is applied to the tissue through the first electrode wherein an action potential is generated in the tissue.

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