Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Silicon containing doai
Patent
1985-01-14
1986-05-13
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Silicon containing doai
514460, 514470, 549214, 549415, 549465, A61K 31557, A61K 3134, C07D307935
Patent
active
045887136
ABSTRACT:
Compounds of the formula ##STR1## are disclosed wherein R.sup.1 stands for hydrogen, C.sub.1-4 straight or branched alkyl or pharmacologically acceptable cation,
R.sup.2 stands for hydrogen, C.sub.1-4 alkanoyl, benzoyl, or benzoyl substituted by C.sub.1-4 alkyl or halogen, and R.sup.2 can further represent tetrahydropyranyl, trialkylsilyl or alkoxyalkyl,
A stands for ethylene, cis or trans-vinylene or --C.dbd.C--,
n may represent 2, 3 or 4. The compounds are highly effective in the inhibition of thrombocyte aggregation while at the same time exert only a very small hypotensive effect.
Dorman Gyorgy
Galambos Geza
Gyory Peter
Ivanics Jozsef
Kanay Karoly
Chinoin Gyogyszer Vegyeszeti Termekek Gyara Rt.
Dentz Bernard I.
Dubno Herbert
Jiles Henry R.
Ross Karl F.
LandOfFree
Selective biologically active 7-oxo-prostacyclin derivatives and does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Selective biologically active 7-oxo-prostacyclin derivatives and, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Selective biologically active 7-oxo-prostacyclin derivatives and will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1770194