Selective beta-2 adrenergic antagonists for the treatment of gla

Details Selective beta-2 adrenergic antagonists for the treatment of gla Selective beta-2 adrenergic antagonists for the treatment of gla

1982-04-14

1984-09-04

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 31135

Patent

active

044697066

ABSTRACT:
A method of decreasing the intraocular pressure in the eye of an animal which comprises administering to the animal an intraocular pressure decreasing amount of a beta.sub.2 adrenergic receptor antagonist having a .beta..sub.2 /.beta..sub.1 potency ratio of at least 25. The method is particularly useful for the treatment of glaucoma in humans.

REFERENCES:
patent: 3989844 (1976-11-01), Schutz et al.
patent: 4402976 (1983-09-01), Muir
Brit. J. Ophthal. 59, 296-300, (1975)-Elliott et al.
Brit. J. Ophthal. 59, 301-303, (1975)-Bonomi et al.
Invest. Ophthal. 15(6), (1976), pp. 489-492-Katz et al.
Invest. Ophthal. & Visual Sci. 21(6), 798-804, (1981)-Nathanson.
Brit. J. Pharmacol., (1980)-292-293, (1980)-Bilski et al.
Brit. J. Pharmacol. 73, 97-100, (1981)-Nathanson.

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