Selective beta-2 adrenergic antagonists for the treatment of gla

Details Selective beta-2 adrenergic antagonists for the treatment of gla Selective beta-2 adrenergic antagonists for the treatment of gla

1980-11-07

1987-03-24

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514913, A61K 3115

Patent

active

046525866

ABSTRACT:
A method of decreasing the intraocular pressure in the eye of an animal which comprises administering to the animal an intraocular pressure decreasing amount of a beta.sub.2 adrenergic receptor antagonist having a .beta..sub.2 /.beta..sub.1 potency ratio of at least 10. The method is particularly useful for the treatment of glaucoma in humans.

REFERENCES:
patent: 3989844 (1976-11-01), Schutz et al.
Brit. J. Ophthal., 59 296-300 (1975)--Elliot et al.
Brit. J. Ophthal., 59, 301-303 (1975)--Bonomi et al.
Invest. Ophthal., 15(6) (1976), pp. 489-492--Katz et al.
Zimmerman et al., Survey of Ophthalmology, 23: 347-362 (1977).

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