Selective administration of drug with ocular therapeutic system

Details Selective administration of drug with ocular therapeutic system Selective administration of drug with ocular therapeutic system

1979-04-23

1980-01-29

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

128260, 424 16, 424 19, 424 21, 424 22, 424 28, A61K 922, A61M 3100

Patent

active

041861841

ABSTRACT:
A method for administering a drug to a preselected tissue compartment of the eye for advantageously controlling the concentration of drug in the tissue compartment is disclosed. The method comprises (1) placing an ocular therapeutic system in the eye, and (2) orienting the drug releasing portal of the system towards the preselected tissue compartment for controlled administration of drug thereto.

REFERENCES:
J. Shell & R. Baker, Diffusional Systems for Controlled Release of Drugs to the Eye, Ann. Ophthalmol. 6:1037 (1974).
J. Shell, Ocular Therapy by Controlled Drug Delivery: the Ocusert System, Ophthalmic Surg, 5:73 (1974).
H. Armaly and K. Rao, The Effect of Pilocarpine Ocusert with Different Release Rates on Ocular Pressure, Invest. Ophthalmol. 12, 491 (1973).
V. A. Place, M. Fisher, S. Herbst, L. Gordon & R. C. Merrill, Comparative Pharmacologic Effects of Pilocarpine Administered to Normal Subjects by Eyedrops or by Ocular Therapeutic Systems, Amer. J. Ophthalmol. 80, 706 (1975), (above cited as footnotes #23-#26, p. 592).
S. K. Chandrasekaran, Harriet Benson & John Urquhart, Alza Corp., Palo Alto, Calif., Chapter 7, "Methods to Achieve Controlled Drug Delivery-The Biomedical Engineering Approach", pp. 557-572, 590-591.
Robinson, J. R. Ed., "Sustained & Controlled Release Drug Delivery Systems, Marcel Dekker, Inc. N.Y., N.Y. (1978).

Affiliated with

Also associated with

Rating

Selective administration of drug with ocular therapeutic system does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Selective administration of drug with ocular therapeutic system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Selective administration of drug with ocular therapeutic system will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-881679