Combinatorial chemistry technology: method – library – apparatus – Method specially adapted for identifying a library member – Direct analysis of a library member – per se – by a physical...
Reexamination Certificate
2000-11-10
2008-10-28
Epperson, Jon D. (Department: 1639)
Combinatorial chemistry technology: method, library, apparatus
Method specially adapted for identifying a library member
Direct analysis of a library member, per se, by a physical...
C506S009000, C506S014000, C435S006120
Reexamination Certificate
active
07442159
ABSTRACT:
The present invention concerns a method for the selection of a virus comprising the steps of: (a) providing a virus encoding and displaying a fusion polypeptide, said fusion polypeptide comprising a heterologous polypeptide inserted into the sequence of a viral coat protein polypeptide, wherein said virus comprises a cleavable site located within a displayed polypeptide; (b) exposing the virus to a cleaving agent; (c) propagating the virus comprising intact fusion protein.
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Jestin Jean-Luc
Kristensen Peter
Riechmann Lutz
Winter Gregory Paul
Domantis Limited
Edwards Angell Palmer & & Dodge LLP
Epperson Jon D.
Steele Amber D.
Williams Kathleen
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