Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Reexamination Certificate
2006-03-14
2006-03-14
Richter, Johann (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
C540S465000, C540S470000, C540S455000, C540S463000, C534S016000, C534S015000, C534S014000, C534S010000, C424S009200
Reexamination Certificate
active
07012140
ABSTRACT:
The present invention is directed, in general, to a contrast agent comprising a tetraazacyclododecane ligand and comprising a macrocyclic ring and a paramagnetic metal ion coordinated to the tetraazacyclododecane ligand. Pendent arms R, R′, R″ and R′″ attached to a ring nitrogen. The pendent arms have the general formula: −C′HR1R2and for three or more of the pendant arms a chirality of the carbon atoms C′ are identical for each of three or more of the pendant arms. The R1group is larger than hydrogen and R2is selected from the group consisting of: an alcohol, amides, a carboxylate, phosphinates and a phosphonate. One or more substituents R6is a group larger than a methyl group and is located on one or more ring carbons.
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Kovacs Zoltan
Sherry A. Dean
Woods Mark
Board of Regents , The University of Texas System
Macrocyclics
Nwaonicha Chukwuma
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