Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-12-11
2007-12-11
Vogel, Nancy (Department: 1636)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S006120, C435S254110, C435S320100
Reexamination Certificate
active
10508694
ABSTRACT:
It is intended to provide a selection marker gene with the use of auxotrophy as an indication which is usable in transforming a fungus. Namely, a selection marker comprising a quinolinate phosphoribosyltransferase gene isolated fromAspergillus oryzae.
REFERENCES:
patent: 2000-308491 (2000-11-01), None
patent: WO 00/56762 (2000-09-01), None
Panozzo et al. Aerobic and anaerobic NAD+ metabolism inSaccharomyces cerevisiae. FEBS Letters 517: 97-102. 2002.
P.J. Punt, et al.; “Transformation ofAspergillusbased on the hygromycin B resistance marker fromEscherichia coli”; Gene; vol. 56; 1987; pp. 117 and 119-124./Discussed in the specification.
T. Kubodera, et al.; “Pyrithiamine Resistance Gene (ptrA) ofAspergillus oryzae: Cloning, Characterization and Application as a Dominant Selectable Marker for Transformation”;Biosci. Biotechnol. Biochem.; vol. 64; No. 7; 2000; pp. 1416-1421./Discussed in the specification.
K. Gomi, et al.; “Integrative Transformation ofAspergillus oryzaewith a Plasmid Containing theAspergillus nidulans argBGene”;Agric. Biol. Chem.; vol. 51; No. 9; 1987; pp. 2549-2555./Discussed in the specification.
S.E. Unkles, et al.; “TheAspergillus niger niaDgene encoding nitrate reductase: upstream nucleotide and amino acid sequence comparisons”;Gene; vol. 111; 1992; pp. 149-155./Discussed in the specification.
Y. M.J.T. de Ruiter-Jacobs, et al; “A gene transfer system based on the homologouspyrGgene and efficient expression of bacterial genes inAspergillus oryzae”; Curr Genet; vol. 16; 1989; pp. 159-163./Discussed in the specification.
K. Iwai, et al.; “Distribution of Quinolinate Phosphoribosyl-Transferase in Animals, Plants and Microorganisms”;J. Nutr. Sci. Vitaminol.; vol. 19; 1973; pp. 491-499./Cited in the International Search Report.
H-K. Chang, et al.; “Role of Quinolinate Phosphoribosyl Transferase in Degradation of Phthalate byBurkholderia cepaciaDBO1”;Journal of Bacteriology; vol. 181; No. 10; May 1999; pp. 3069-3070 and 3072-3075./Cited in the International Search Report.
R. Bhatia et al.; “The Sequencing, Expression, Purification, and Steady-State Kinetic Analysis of Quinolinate Phosphoribosyl Transferase fromEscherichia coli”; Archives of Biochemistry and Biophysics; vol. 325; No. 2; Jan. 15, 1996; pp. 270-278./Cited in the International Search Report.
Punt et al.; “Transformation ofAspergillusbased on the hygromycin B resistance marker fromEscherichia coli”; Gene; vol. 56; 1987; pp. 117-124; discussed in the specification.
Chang et al.; “Role of Quinolinate Phosphoribosyl Transferase in Degradation ofPhthalate byBurkholderia cepaciaDBO1”; Journal of Bacteriology; vol. 181; No. 10; May 1999; pp. 3069-3075; cited in the International Search Report.
Cullen, Daniel, et al. “Controlled Expression and Secretion of Bovine Chymosin inAspergillus nidulans ;” Bio/Techinology, vol. 5, pp. 369-376. (Apr. 1987).
Ballance, D. J., et al. “Development of a high-frequency transforming vector forAspergillus nidulans,” Gene, 36, pp. 321-331. (1985).
Tsukagoshi, Norihiro, et al. “Isolation of a cDNA encodingAspergillus oryzaeTaka-amylase A: evidence for multiple related genes;”Gene, 84, pp. 319-327. (1989).
Kato, M., et al. “AnAspergillus nidulansnuclear protein, AnCP, involved in enhancement of Taka-amylase A gene expression, binds to the CCAAT-containingtaaG2, amdS,andgatApromoters;”Mol Gen Genet, 254, pp. 119-126. (1997).
Kato, N., et al. “Isomaltase formed by α-glucosidases triggers amylase induction inAspergillus nidulans;” Curr Genet, 42, pp. 43-50. (2002).
Kato, M., et al. “No Factors Except for the Hap Complex increase the Taka-amylase A Gene Expression by Binding to the CCAAT Sequence in the Promoter Region;”Biosci. Biotechnol. Biochem., 65 (10), pp. 2340-2342. (2001).
Tani, S., et al. “In Vivo and in Vitro Analyses of the AmyR Binding Site of theAspergillus nidulansagdA Promoter; Requirement of the CGG Direct Repeat for Induction and High Affinity Binding of AmyR;”Biosci. Biotechnol. Biochem., 65 (7), pp. 1568-1574. (2001).
Berka, R. M., et al.; “Aspergillus oryzaeEST SEQ ID No. 5364;”(2001) XP-002381185.
Berka, R. M., et al.; “Aspergillus oryzaeEST SEQ ID No. 4947;”(2002) XP-002381186.
“Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase);” (1995) XP-022381187.
“Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (QPRTase);” (1997) XP-002381188.
The European Search Report dated Jul. 15, 2006, citing references AE, AF, AG & AH.
Amano Enzyme Inc.
Edwards Angell Palmer & & Dodge LLP
Joike Michele K.
Vogel Nancy
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