Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1992-06-30
1994-10-04
Wax, Robert A.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
435 691, 435198, 4351723, 435874, 435877, 935 10, 536 232, C12N 1510, C12N 1555, C12N 1500, C12N 920
Patent
active
053525949
ABSTRACT:
The invention relates to methods of making and selecting esterase enzymes having an improved perhydrolysis to hydrolysis ratio, and varying K.sub.cat, K.sub.m, and K.sub.cat /K.sub.m and substrate specificity. Such enzymes are useful in peracid bleaching systems and other applications.
REFERENCES:
patent: 3974082 (1976-08-01), Weyn
patent: 4760025 (1988-07-01), Estell et al.
patent: 4981611 (1991-01-01), Kolattukudy et al.
patent: 5030240 (1991-07-01), Wiersema et al.
patent: 5108457 (1992-04-01), Poulose et al.
Jordan, F. et al., "Proton Nuclear Magnetic Resonance . . . Thiolsubtilisins", Biochemistry, vol. 20, pp. 6366-6370, 1981.
Wright, C. S. et al., "Structure of Subtilisin BPN' at 2.5 .ANG. Resolution," Nature, vol. 221, pp. 235-242, 1969.
Winter, G. et al., "Redesigning Enzyme Structure . . . ," Nature, vol. 299, pp. 235-242, 1969.
Rasketter, W. H., "Enzyme engineering: Applications and promise," Trends in Biotech., vol. 1, pp. 80-84, 1983.
Robertus, J. D., "An X-Ray Crystallographic Study of the Binding . . . BPN'", Biochemistry, vol. 11, No. 13, pp. 2439-2449, 1972.
Koller, W. et al. "Mechanism of Action of Cutinase: Chemical Modification of the Catalytic Triad Characteristic for Serine Hydrolases," Biochemistry, vol. 21, pp. 3083-3090, 1982.
Nedkov, P. et al., "Die Primarstruktur von Subtilisin DY", Hoppe-Seyler's Z. Physiol. Chem., bd 364, pp. 1537-1540, 1983.
Svendsen, I., "Chemical Modifications of the Subtilisins with Special Reference to the binding of Large Substrates. A Review", Carlsberg Res. Sommun, vol. 41, pp. 237-291, 1976.
Glaser, A., "Transesterification Reactions Catalyzed by Subtilisins," J. Biol. Chemistry, vol. 241, pp. 635-638, 1966.
J. E. Fulton et al. "The Glycerol Ester Hydrolase from Corynebacterium acnes: A Serine Hydrolase" Biochemistry 13(11) 2320-2327 (1974).
A. Atev. et al. "Isolation of Candida lipolytica mutants with Increased Lipase Activity" Chemical Abstracts. 87:212 Ab. #50085.
W. Kugimiya et al. "Molecular Cloning and Nucleotide Sequence of the Lipase Gene from Pseudomonas fragi." Biochem. Biophys. Res. Commun. 141:185-190 (Nov. 1986).
F. Gotz et al. "Complete Nucleotide Sequence of the Lipase Gene from Staphlococcus . . . " Nuc. Acids Res. 13(16) 5895-5906 (Aug. 1985).
A. J. P. Docherty et al. "Molecular Cloning and Nucleotide Sequence of the Rat Lingual lipose cDNA" Nuc. Acids. Res. 13(6) 1891-1903 (Mar. 1985).
J. McLean et a. "Cloning and Expression of Human Lecithin-Cholesterol Acyltransferase cDNA". Proc. Natl. Acad. Sci. 83:2335-2339 (Apr. 1986).
Genecor, Inc.
Horn Margaret A.
Prouty Rebecca
Wax Robert A.
LandOfFree
Selection and method of making enzymes for perhydrolysis system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Selection and method of making enzymes for perhydrolysis system , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Selection and method of making enzymes for perhydrolysis system will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-580812