Selecting goat erythrocytes to simulate human platelets in hemat

Details Selecting goat erythrocytes to simulate human platelets in hemat Selecting goat erythrocytes to simulate human platelets in hemat

1979-05-07

1981-04-28

Fagelson, Anna P.

Compositions

Nonreactive analytical, testing, or indicating compositions

424 3, 424 9, 424 12, 435 2, G01N 3348, G01N 3500

Patent

active

042644704

ABSTRACT:
A method is described for preparing a human platelet analog for use as a reference control in particle analysis instrumentation of the Coulter type. Goat erythrocytes from individual goats which have been selected with respect to age, sex, selective breeding, a controlled environment, prior veterinary treatment, and diet are altered in size and/or combined with samples from several goats, as needed, to obtain a blend for use as a reference control for automated particle counting equipment in which the goat erythrocytes simulate in number, size and distribution the platelets in human whole blood. The controls are useful as a free-standing reference for determination of human platelets only, or can be added to whole blood reference controls for multi-parameter instruments.

REFERENCES:
patent: 3553310 (1971-01-01), Csizmas
patent: 4157383 (1979-06-01), Sedlacek
patent: 4160644 (1979-07-01), Ryan
patent: 4179398 (1979-12-01), Hunt

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