Selectin variants

Details Selectin variants Selectin variants

1994-07-13

1997-01-14

Draper, Garnette D.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

530395, 536 231, 536 235, 435 691, 4351723, 4352523, 4353201, 514 8, 935 10, C12N 510, C07K 14435

Patent

active

055938825

ABSTRACT:
This invention concerns selectin variants having an amino acid alteration at a site or sites of a selectin lectin domain amino acid sequence within a region defined by binding sites recognized by blocking monoclonal antibodies to the corresponding selectin unaltered in the lectin domain. Nucleotide sequences encoding such variants, expression vectors containing such nucleotide sequences, end host cells transformed with such expression vectors are also within the scope of the invention.

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