Selected immunoconjugates for binding to aminophospholipids

Details Selected immunoconjugates for binding to aminophospholipids Selected immunoconjugates for binding to aminophospholipids

2003-08-15

2009-11-10

Goddard, Laura B (Department: 1642)

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

C424S181100, C424S183100

Reexamination Certificate

active

07615223

ABSTRACT:
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.

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