Chemistry: electrical and wave energy – Apparatus – Coating – forming or etching by sputtering
Patent
1991-03-22
1992-01-07
Tung, T.
Chemistry: electrical and wave energy
Apparatus
Coating, forming or etching by sputtering
2041828, 436 71, G01N 2726
Patent
active
050788531
ABSTRACT:
A diagnostic device is provided where the preferred embodiment is useful for sorting seric or plasmatic lipoproteins into four cholesterol fractions. The device comprises a plurality of gel matrixes, preferably agarose-based, defining a liquid pathway upon which a directioinal electrophoretic gradient can be imposed. The gel matrixes are in a serial relationship and preferably are of a successively decreasing pore size from a most upstream matrix to a most downstream matrix. In a preferred embodiment the three more downstream gel matrixes are in a noncontiguous relationship and are separated by interfaces containing buffer. These interfaces are adapted to receive a separate lipoprotein fraction upon reversal of the electrophoretic gradient direction.
REFERENCES:
patent: 3620947 (1971-11-01), Allen et al.
patent: 3844925 (1974-10-01), Stathakos
patent: 4189370 (1980-02-01), Boschetti
Cobb and Sanders, "Enzymic Determination of Cholesterol in Serum Lipoproteins Separated by Electrophoresis", Clin. Chem., 24/7, 115-1120 (1978).
Muniz, "Measurement of Plasma Lipoproteins by Electrophoresis on Polyacrylamide Gel", Clin Chem., 23/10, 1825-1833 (1977).
Serwer, "Agarose Gels: Properties and Use for Electrophoresis", Electrophoresis, vol. 4, pp. 375-382 (1983).
Serwer et al., "Agarose Gel Electrophoresis of Bacteriophages and Related Particles . . .", Electrophoresis, vol. 4, 233-236 (1983).
Chang Joyce
Manning Charles R.
Pinto LeRoy J.
Assay Technology, Inc.
Ryser David G.
Tung T.
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