Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone
Reexamination Certificate
1999-10-13
2003-11-25
Willse, David H. (Department: 3738)
Prosthesis (i.e., artificial body members), parts thereof, or ai
Implantable prosthesis
Bone
C623S016110, C623S018110, C606S060000
Reexamination Certificate
active
06652592
ABSTRACT:
1.0 FIELD OF THE INVENTION
This invention relates to a device made from segmentally demineralized and appropriately shaped and machined bone for implantation as a ligament, tendon, support or in any other application in which an implant having at least one rigid segment and at least one flexible segment, is required.
1.1 BACKGROUND
There is a continuing need in the art for biologically acceptable ligament or tendon replacements. Various efforts have been made in the art to accommodate this need. For example, in U.S. Pat. No. 5,053,049, a flexible prosthesis of predetermined shape and a process for making said prosthesis was disclosed. According to that disclosure, a flexible biocompatible and non-antigenic prosthesis for replacement of a cartilaginous part was prepared by machining bone into a desired shape corresponding to the shape of a cartilaginous body part to be replaced, demineralization of the bone to impart flexibility, and tanning to reduce antigenicity. There was no disclosure or suggestion of using the demineralized bone as a tendon or ligament replacement.
In U.S. Pat. No. 5,092,887, a method for replacement or augmentation of a damaged fibrous connective tissue was disclosed wherein a ligament made from a segment of bone that had been demineralized was attached between first and second body parts. There was no disclosure or suggestion of machining the bone prior to demineralization to produce fixation ends thereon, and demineralization of only a segment of the thus machined bone to produce a flexible segment, while leaving the machined attachment ends in a fully mineralized and rigid state for fixation directly to bone adapted to receive such fixation ends. The disclosure in the U.S. Pat. No. 5,092,887 with respect to its discussion of background art and methods of demineralization of bone is hereby incorporated by reference.
2.0 SUMMARY OF THE INVENTION
This invention provides a novel bone implant having at least one rigid, mineralized bone segment, which may be machined to include threads, grooves, a driver head, a recess or a symmetric or asymmetric shape, and at least one flexible, demineralized segment, which may also be machined to any desired shape prior to demineralization, or after demineralization.
REFERENCES:
patent: 3772709 (1973-11-01), Swanson
patent: 3875594 (1975-04-01), Swanson
patent: 3886600 (1975-06-01), Hahn et al.
patent: D277509 (1985-02-01), Lawrence et al.
patent: D277784 (1985-02-01), Sgarlato et al.
patent: 4553272 (1985-11-01), Mears
patent: D284099 (1986-06-01), Laporta et al.
patent: 4627853 (1986-12-01), Campbell et al.
patent: 4743259 (1988-05-01), Bolander et al.
patent: 4759768 (1988-07-01), Hermann et al.
patent: 4772286 (1988-09-01), Goble
patent: 4839215 (1989-06-01), Starling et al.
patent: 4871367 (1989-10-01), Christensen et al.
patent: 4932973 (1990-06-01), Gendler
patent: 5053049 (1991-10-01), Campbell et al.
patent: 5092887 (1992-03-01), Gendler
patent: 5092896 (1992-03-01), Meuli et al.
patent: 5133761 (1992-07-01), Krouskop
patent: 5171273 (1992-12-01), Silver et al.
patent: 5192322 (1993-03-01), Koch et al.
patent: 5292349 (1994-03-01), Foresti
patent: 5405390 (1995-04-01), O'Leary et al.
patent: 5405400 (1995-04-01), Linscheid et al.
patent: 5484443 (1996-01-01), Pascarella et al.
patent: 5507813 (1996-04-01), Dowd et al.
patent: 5676146 (1997-10-01), Scarborough
patent: 5919234 (1999-07-01), Lemperle et al.
patent: 6123731 (2000-09-01), Boyce et al.
patent: 6200347 (2001-03-01), Anderson et al.
patent: 2001/0020188 (2001-09-01), Sander
patent: 0356112 (1990-02-01), None
patent: 0483944 (1992-05-01), None
patent: WO93/15694 (1993-08-01), None
patent: WO97/25941 (1997-07-01), None
patent: WO97/25945 (1997-07-01), None
patent: WO 99 21515 (1999-05-01), None
patent: WO 99 38453 (1999-08-01), None
patent: WO 00 40179 (2000-07-01), None
patent: WO 01/49219 (2001-07-01), None
International Search Report, attached to International Application No. PCT/US02/04980, dated Nov. 5, 2002.
Jackson, Douglas W. et al., Biologic remodeling after anterior cruciate ligament reconstruction using a collagen matrix derived from demineralized bone: An expermental study in the goat model, 1996, Am J. Sports Med. 24(4):405-414.
Bianchi John
Buskirk Dayna
Carter Kevin C.
Grooms Jamie M.
Sander Thomas W.
Chattopadhyay Urmi
McAndrews Held & Malloy Ltd.
Pochopien Donald J.
Regeneration Technologies, Inc.
Willse David H.
LandOfFree
Segmentally demineralized bone implant does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Segmentally demineralized bone implant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Segmentally demineralized bone implant will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3122094