Secretory leukocyte protease inhibitor as an inhibitor of trypta

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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435226, 530324, 930250, A61K 3857, C07K 1481, C12N 964

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active

056332270

ABSTRACT:
This invention concerns methods of treating mast-cell mediated conditions in mammals, the methods comprising administering to the mammals pharmacologically active fragments or muteins of SLPI; methods of treating asthma or allergic rhinitis in mammals, the methods comprising administering to the mammals SLPI or pharmacologically active fragments or muteins thereof; methods for inhibiting tryptase; methods for identifying inhibitors of tryptase; and certain fragments and muteins of SLPI.

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