Secretion of insulin-like growth factor-I

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 691, 435 698, 4351723, 43525233, 4353201, 530303, 530324, 530399, 530808, 935 48, C12P 2102, C12N 1500, C12N 120

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050843842

ABSTRACT:
A method for bacterially producing IGF-I is disclosed in which Gram-negative bacteria are caused to express a gene consisting of a lamB or ompF signal sequence operatively joined to a DNA sequence encoding IGF-I and producing IGF-I which is secreted into the periplasmic space of the bacteria.

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