Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-02-06
1998-05-19
Ketter, James
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4351723, 536 231, C12N 1566, C12N 1511, C12P 2102
Patent
active
057534624
ABSTRACT:
Expression vectors and methods for cloning amino-terminal signal sequences are disclosed. These vectors and methods are useful tools for cloning, identifying and isolating previously unknown signal sequences. In turn, an orphan signal sequence can be used to clone, identify and isolate the corresponding orphan proteins that the orphan signal sequence directs to the surface of a cell. Using these expression vectors and methods, an orphan protein can be cloned in the absence of a functional assay that detects such protein.
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Brusca John S.
Ketter James
Sleath Janet
Speckman Ann W.
ZymoGenetics Inc.
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