Secretin intermediates and derivatives

Chemistry of carbon compounds – Miscellaneous organic carbon compounds

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2601125R, 424 1, C07C10352, C07G 700

Patent

active

039870146

ABSTRACT:
[6-TYR] Secretin is biologically active and can be radio-iodinated for use in the radioimmunoassay of secretin. The peptide can be produced by solid phase synthesis using benzhydrylamine resin as the support.

REFERENCES:
patent: 3812091 (1974-05-01), Ondetti
Bodansky et al., J. Am. Chem. Soc., 91, 944-949 (1969).
Bodanszky et al., J. Am. Chem. Soc., 89, 6753-6757 (1967).
Bodanszky et al., J. Am. Chem. Soc., 89, 685-689 (1967).
Bayer et al., Hoppe-Seyler's Zeit. Physiol. Chem., 352, 759-760 (1971).
J. M. Stewart and J. D. Young, "Solid Phase Peptide Synthesis," Freeman and Co., San Francisco (1969), pp. 1-13.
Pietta et al.: Chem. Comm., 1970, 650-651.

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