Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2007-04-17
2007-04-17
Nickol, Gary (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S387300, C530S350000, C536S023500
Reexamination Certificate
active
10063582
ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
REFERENCES:
patent: 5536637 (1996-07-01), Jacobs
patent: 5639597 (1997-06-01), Lauffer et al.
patent: 5994088 (1999-11-01), Mechetner et al.
patent: 6008325 (1999-12-01), Risteli et al.
patent: 6024955 (2000-02-01), Asano et al.
patent: 6025156 (2000-02-01), Gwynn et al.
patent: 6124433 (2000-09-01), Falb et al.
patent: 6156500 (2000-12-01), Falb
patent: 6162604 (2000-12-01), Jacob
patent: 6228582 (2001-05-01), Rodier et al.
patent: 6395306 (2002-05-01), Cui et al.
patent: 6414117 (2002-07-01), Levinson
patent: 6465185 (2002-10-01), Goldfine et al.
patent: 6498235 (2002-12-01), Sheppard et al.
patent: 6562343 (2003-05-01), Levinson
patent: 6645499 (2003-11-01), Lal et al.
patent: 6730502 (2004-05-01), Van Hijum et al.
patent: 6737522 (2004-05-01), Sundick et al.
patent: WO 97/38085 (1997-10-01), None
Kitagawa et al. (2001), J. Biol. Chem. 276(42): 38721-38726.
Osada et al., NCBI Accession No. BAB03554, Aug. 1, 2000, hypothetical protein [Macaca fascicularis].
Wang et al., Trends in Pharm. Sci., 17 : 276-279, 1996.
Bustin et al., TRENDS in Molec. Med. 8(6): 269-272, 2002.
Saito-Hisaminato et al., DNA Res., 9:35, 2002.
Klein et al. Selection for Genes Encoding Secreted Proteins and Receptors.Proc. Natl. Acad. Sci., 93:7108-7113 (1996).
Database Search, DNA Sequence Alignments [BLASTN 2.2.1[Jul. 12, 2001], NCBI].
Database Search, Protein Sequence Alignments [BLASTN 2.2.1 [ Jul. 12, 2001], NCBI].
Allman, et al. 1996. BCL-6 expression during B-cell activation.Blood, 87(12):5257-5268.
Chen, et al. 2002. Discordant protein and mRNA expression in lung adenocarcinomas.Molecular&Cellular Proteomics 1.4, pp. 304-313.
Fessler, et al. 2002. A genomic and proteomic analysis of activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-activated protein kinase.The Journal of Biological Chemistry, 277(35):31291-31302.
Fu, et al. 1996. Translational regulation of human p53 gene expression.The EMBO Journal, 15(16):4392-4401.
Gökmen-Polar, et al. 2001. Elevated protein kinase C βII is an early promotive event in colon carcinogenesis.Cancer Research, 61:1375-1381.
Hanash, S. 2003. Making sense of microarray data to classify cancer.The Pharmacogenomics Journal, 3:308-311.
Hanash, S. Mar. 2005. Integrated global profiling of cancer.Nature Reviews, Applied Proteomics Collection, pp. 9-14.
Hancock, W. S. 2004. Do we have enough biomarkers?Journal of Proteome Research, 3(4):685.
Haynes, et al. 1998. Proteome analysis: Biological assay or data archive?Electrophoresis, 19:1862-1871.
Hu, et al. 2003. Analysis of genomic and proteomic data using advanced literature mining.Journal of Proteome Research, 2:405-412.
Jang, et al. 1997. An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastatis-associated genes in murine tumor cells.Clin. Exp. Metastasis, 15(5):469-483. (Abstract).
Konopka, et al. 1986. Variable expression of the translocatedc-abloncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients.Proc. Natl. Acad. Sci. USA, 83:4049-4052.
Ohara, et al. 2001. Directional cDNA library construction assisted by the in vitro recombination reaction.Nucleic Acids Research, 29(4):e22 p. 1-8.
Powell, et al. 1998. Expression of cytochrome P4502E1 in human liver: Assessment by mRNA, genotype and phenotype.Pharmacogenetics, 8:411-421. (Abstract).
Tokunaga, et al. 2000. Application of quantitative RT-PCR using “TaqMan” technology to evaluate the expression of CK 18 mRNA in various cell lines.J. Exp. Clin. Cancer Res., 19(3):375-381.
Vallejo, et al. 2000. Evidence of tissue-specific, post-transcriptional regulation of NRF-2 expression.Biochimie, 82(12):1129-1133. (Abstract).
2002-2003 Catalog & Technical Reference, New England BioLabs, Inc., p. 122.
Abe, et al. “An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue.”Br J Cancer. Dec. 1, 2003;89(11):2104-9. (Abstract Only).
Alberts, et al. 1994.Molecular Biology of the Cell, 3rd Edition, pp. 403-404, 453. New York: Garland Publishing.
Alberts, et al. 1994.Molecular Biology of the Cell, 3rd Edition, pp. 1216-1217. New York: Garland Publishing.
Alberts, et al. 2002.Molecular Biology of the Cell 4th Edition, pp. 302, 363-364, 379, 435. New York: Garland Publishing.
Anderson, et al. 1997. A comparison of selected mRNA and protein abundances in human liver.Electrophoresis, 18:533-537.
Ando, et al. “Selective apoptosis of natural killer-cell tumours by I-asparaginase.”Br. J. Haematol. Sep. 2005;130(6):860-8. (Abstract Only).
Aust, et al. “Human thyroid carcinoma cell lines and normal thyrocytes: expression and regulation of matrix metalloproteinase-1 and tissue matrix metalloproteinase inhibitor-1 messenger-RNA and protein.”Thyroid. Oct. 1997;7(5):713-24. (Abstract Only).
Barnes, et al. “Expression of embryonic fibronectin isoform EIIIA parallels alpha-smooth muscle actin in maturing and diseased kidney.”J Histochem Cytochem. Jun. 1999;47(6):787-98. (Abstract Only).
Bea, et al. “BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas.”Cancer Res. Mar. 15, 2001;61(6):2409-12. (Abstract Only).
Blaschke, et al. “Rapid quantitation of proinflammatory and chemoattractant cytokine expression in small tissue samples and monocyte-derived dendritic cells: validation of a new real-time RT-PCR technology.”J Immunol Methods. Dec. 1, 2000;246(1-2):79-90. (Abstract Only).
Buckley, et al. “Butyrate-induced reversal of dexamethasone resistance in autonomous rat Nb2 lymphoma cells.” Apoptosis. 1997;2(6):518-28. (Abstract Only).
Caberlotto, et al. “Alterations in neuropeptide Y levels and Y1 binding sites in the Flinders Sensitive Line rats, a genetic animal model of depression.”Neurosci Lett. Apr. 23, 1999;265(3):191-4.
Caberlotto, et al. “Neurokinin 1 receptor and relative abundance of the short and long isoforms in the human brain.”Eur J Neurosci. May 2003;17(9):1736-46. (Abstract Only).
Celis, et al. 2000. Gene expression profiling: monitoring transcription and translation products using DNA microarrays and proteomics.FEBS Letters, 480:2-16.
Choi, et al. “Characterization of cyclin D2 expression in human endometrium.” 166:J Soc Gynecol Investig. Jan.-Feb. 2002;9(1):41-6. (Abstract Only).
Couvelard, et al. “Human chorionic gonadotrophin beta expression in malignant Barrett's oesophagus.”Virchows Arch. Sep. 2004;445(3):279-84. Epub Aug. 10, 2004. (Abstract Only).
Crick, F. 1970. Central dogma of molecular biology.Nature, 227:561-563.
Dagenais, et al. “Downregulation of ENaC activity and expression by TNF-alpha in alveolar epithelial cells.”Am J Physiol Lung Cell Mol Physiol. Feb. 2004;286(2):L301-11. Epub Sep. 26, 2003. (Abstract Only).
de Boer, et al. “Involvement of the CCND1 gene in hairy cell leukemia.”Ann Oncol. Mar. 1996;7(3):251-6. (Abstract Only).
Debieve, et al. “Inhibin and activin production and subunit expression in human placental cells cultured in vitro.”Mol Hum Reprod. Aug. 2000;6(8):743-9. (Abstract Only).
Dong, et al. “Expression of membrane-type matrix metalloproteinases 4, 5, and 6 in mouse corneas infected with P. aeruginosa.”Invest Ophthalmol Vis Sci. Dec. 2001;42(13):3223-7. (Abstract Only).
Duchrow, et al. “Assessment of proliferative activity in colorectal carcinomas by quantitative reverse transcriptase-po
Goddard Audrey
Godowski Paul J.
Grimaldi J. Christopher
Gurney Austin L.
Wood William I.
Barnes Elizabeth M.
Chandra Gyan
Genentech
Knobbe Martens Olson & Bear LLP
Kresnak Mark T.
LandOfFree
Secreted and transmembrane polypeptides and nucleic acids... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Secreted and transmembrane polypeptides and nucleic acids..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Secreted and transmembrane polypeptides and nucleic acids... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3743773