Secreted and transmembrane polypeptides and nucleic acids...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.

Reexamination Certificate

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C530S350000, C530S300000, C530S866000

Reexamination Certificate

active

07119177

ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

REFERENCES:
patent: 6485938 (2002-11-01), Sheppard et al.
patent: 2002/0172678 (2002-11-01), Ferrara et al.
patent: 0 607 054 (1994-07-01), None
patent: 0 834 563 (1998-04-01), None
patent: 1 033 401 (2000-09-01), None
patent: WO 97/07198 (1997-02-01), None
patent: WO 98/39448 (1998-09-01), None
patent: WO 98/42741 (1998-10-01), None
patent: WO 99/06550 (1999-02-01), None
patent: WO 99/46375 (1999-09-01), None
patent: WO 99/53040 (1999-10-01), None
patent: WO 99/63083 (1999-12-01), None
patent: WO 99/63088 (1999-12-01), None
patent: WO 00/08145 (2000-02-01), None
patent: WO 00/52022 (2000-09-01), None
patent: WO 00/53753 (2000-09-01), None
patent: WO 00/70049 (2000-11-01), None
patent: WO 01/36465 (2001-05-01), None
patent: WO 01/57190 (2001-08-01), None
Bowie et al. Deciphering the message in protein sequences: tolerance to amino acid substitutions. Science, (Mar. 16, 1990) 247 (4948) 1306-10.
Ngo et al., in The Protein Folding Problem and Tertiary Structure Prediction, Merz and Le Grand (Eds), Aug. 1994, Springer Verlag, pp. 433 and 492-495.
LeCouter et al. Identification of an angiogenic mitogen selective for endocrine gland endothelium. Nature. Aug. 30, 2001;412(6850):877-84.
U.S. Appl. No. 60/165,905.
Tashiro, K., et al. “Signal Sequence Trap: A Cloning Strategy for Secreted Proteins and Type I Membrane Proteins”, vol. 261, Jul. 30, 1993, pp. 600-603.
Joubert, F.J., et al., “The Amino Acid Sequence of Protein a From Dendroaspis Polylepis Polylepis (Black Mamba) Venom”, Hoppe-Seyler's Zeitschrift Fuer Physiologische Chemie, vol. 361, No. 12, 1980, pp. 1787-1794.
Blast Results A1-A44, GenBank.
Blast Results, B1-B5, Dayhoff.
NCBI, Accession No.: AF131820; Direct Submission, Submitted: Feb. 26, 1999, Mei, G., et al.
NCBI, Accession No.: AA865629; National Cancer Institute, 1997, Strausberg, Robert.
NCBI, Accession No.: AA150370; Genome Research, 1996, Hillier, L., et al.
NCBI, Accession No.: AA843667; National Cancer Institute, 1997, Strausberg, Robert.
Brandon, C., “Improved Immunocytochemical Staining Through the Use of Fab Fragments of Primary Antibody, Fab-specific Second Antibody, and Fab-Horseradish Peroxidase”, The Journal of Histochemistry and Cytochemistry, vol. 33, No. 7, pp. 715-719, Jul. 1985.
Klein, R. D., et al., “Selection for Genes Encoding Secreted Proteins and Receptors”, Proceedings of the National Academy of Sciences of USA, No. 93, pp. 7108-7113, Jul. 1996.
Wallin, et al., “Properties of N-Terminal Tails in G-Protein Coupled Receptors: A Statistical Study”, Protein Engineering, vol. 8, No. 7, pp. 693-698, 1995.
Yokohama, -Kobayashi, M., et al., “A Signal Sequence Detection System Using Secreted Protease Activity As An Indicator”, Gene, vol. 163, No. 2, Oct. 3, 1995.
Schnabel, M., et al., “Osteoarthritis and Cartilage”, Journal of the OsteoArthritis Research Society International, —10:62-70 (2002).
Zhang, Yaou, et al., “Versican Modulates Embryonic Chondrocyte Morphology via the Epidermal Growth Factor-like Motifs in G3”, Experimental Cell Research—263:33-42 (2001).

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