Secreted and transmembrane polypeptides and nucleic acids...

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

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C435S254200, C435S320100, C435S325000, C435S358000, C435S361000, C536S023500, C536S024100

Reexamination Certificate

active

07037710

ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

REFERENCES:
patent: WO 99/46281 (1999-09-01), None
Kilty et al. Families of twelve transmembrane domain transporters. Curr Opin Biotechnol. Dec. 1992;3(6):675-82.
Pennica et al. WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. Proc Natl Acad Sci U S A. Dec. 8, 1998;95(25):14717-22.
Konopka et al. Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients. Proc Natl Acad Sci U S A. Jun. 1986;83(11):4049-52.
Hillier et al. WashU-NCI human EST Project. GenBank Database Accession No. AA284298, National Center for Biotechnology Information, Bethesda, MD. Nov. 8, 1997.
Blast Results A1-A3 (Alignment of DNA50988 and various nucleotide sequences—GenBank Database), Oct. 4, 2001.
Blast Results B1-B3 (Alignment of DNA50988 and various polypeptide sequences—Dayhoff Database), Oct. 3, 2001.

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