Secondary shaping of ionically crosslinked polymer compositions

Plastic and nonmetallic article shaping or treating: processes – Mechanical shaping or molding to form or reform shaped article – Plural sequential shaping or molding steps on same workpiece

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264294, 264344, 264347, 6048911, 604265, B29C 3502

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active

057188629

ABSTRACT:
A method for preparing a medical device having the steps: (1) treating an ionically crosslinked hydrogel to strip a substantial amount of the ionic crosslinks while retaining the hydrogel in a desired shape; and (2) ionically re-crosslinking the treated hydrogel of step (1) while retaining the hydrogel in the desired shape. In an exemplary embodiment, a ureteral stent is made by mounting a length of extruded calcium or barium alginate tubing onto a shaping jig and performing secondary shaping to form coil-shaped ends by soaking the mounted robing in a stirred potassium chloride bath, and then soaking it in a calcium chloride bath. The ends readily return after elastic deformation to their coil shapes, with the stent having a permanent memory imposed by the secondary shaping.

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