Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1983-07-14
1986-12-16
Helfin, Bernard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514562, 514567, 514618, 514619, 514620, 560 17, 560 42, 560 43, 562431, 562457, 562442, 562452, 564162, 564165, 564167, C07C10116, C07C101447, A61K 31215, A61K 31195
Patent
active
046297375
ABSTRACT:
A compound of formula (I): ##STR1## or a pharmaceutically acceptable salt, ester or amide thereof, in which: W is an optionally substituted phenyl group of the formula ##STR2## wherein R.sup.1 is hydrogen or fluorine, R.sup.2 is hydrogen, C.sub.1-6 alkyl, halogen or trifluoromethyl; or W is a phenoxymethyl or benzofuran-2-yl group;
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Burger's Medicinal Chemistry, 4th Ed., Part 1 (1980), pp. 167-168.
T. E. Gram, Concepts in Biochemical Pharmacology, Pt. 2, B. B. Brodie and J. R. Gillette, Eds., Springer-Verlage, Berlin (1971), p. 334.
A. Nilsson and B. C. Johnson, Arch. Biochem. Biophys., 101, 494 (1963).
W. J. George and T. R. Tephyl, Mol. Pharmacol., 4, 502, (1968).
Beecham Group p.l.c.
Helfin Bernard
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