Seco-sterol compounds effective in inducing cell differentiation

Details Seco-sterol compounds effective in inducing cell differentiation Seco-sterol compounds effective in inducing cell differentiation

1987-04-30

1990-07-10

Lipovsky, Joseph A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

2603972, 2603975, A61K 3159, C07J 900, C07J 100

Patent

active

049407007

ABSTRACT:
The invention provides new seco-sterol compounds which are effective in inducing the differentiation of malignant cells and are therefore useful for the treatment of malignancies such as leukemia.

REFERENCES:
patent: 4800198 (1989-01-01), DeLuca et al.
Chemical Abstracts, vol. 108 (1988), #180270T, DeLuca et al.
Chemical Abstracts, vol. 107 (1987), #191,147 P, Ostrem et al.
Chemical Abstracts, vol. 106 (1987), #131710M, DeLuca et al.
Frampton et al, "Cancer Research", Sep. 1983, pp. 4443-4447.

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