Sebosuppressive topical cosmetic preparations containing alkoxyb

Details Sebosuppressive topical cosmetic preparations containing alkoxyb Sebosuppressive topical cosmetic preparations containing alkoxyb

1983-12-12

1985-03-05

Killos, Paul J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

560 74, 560 64, C07C 6976

Patent

active

045032440

ABSTRACT:
A topical cosmetic preparation for the treatment of seborrhea containing a sebosuppressively effective amount of at least one alkoxybenzoic acid ester having the formula ##STR1## wherein R.sup.1 represents a C.sub.6-20 -n-alkyl and R.sup.2 is a member selected from the group consisting of --CH.sub.2 OR.sup.3, --C.sub.2 H.sub.4 OR.sup.3, --CH.sub.2 OC.sub.2 H.sub.4 OR.sup.3, --CH.sub.2 OH, --C.sub.2 H.sub.4 OH, --CH(CH.sub.3)OH, --CH.sub.2 NR.sup.3 R.sup.4, --C.sub.2 H.sub.4 NR.sup.3 R.sup.4, --CO.sub.2 R.sup.3 and --CH.sub.2 CO.sub.2 R.sup.3, wherein R.sup.3 and R.sup.4 are C.sub.1-4 -alkyl, as an antiseborrheic, and further containing conventional vehicles and additives for topical application; as well as the process for reducing sebaceous cell sebum production in a mammal in need thereof using the above cosmetic preparation; and the alkoxybenzoic acid esters of the above formula.

REFERENCES:
patent: 2176070 (1939-10-01), Grether et al.
patent: 4138579 (1979-02-01), Chodnekar et al.

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