Sealing device and method for inhibition of flow in capillary me

Chemistry: analytical and immunological testing – Optical result – With claimed manipulation of container to effect reaction or...

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7386402, 422 56, 422 57, 422 58, 422100, 436180, G01N 3122, B01L 1100

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active

052780791

ABSTRACT:
A channel or chamber device having means for inhibiting flow of aqueous medium therein after the channel or chamber has been filled with aqueous medium. The device has a channel or chamber with a sample intake port at one end and an exhaust port at the other end. A restricted or reduced size chamber portion having reduced dimension (height, cross-sectional area or diameter) toward the exhaust port is provided with a water-expandable polymer in the restricted or reduced size chamber portion. The water-expandable polymer inhibits flow or forms a seal in the exhaust port when the polymer is contacted with an aqueous medium. The channel or chamber device having means for inhibiting flow of aqueous medium therein is especially adaptable to capillaries used in medical diagnostic measuring devices which contain an analytical reagent for biological fluids, such as saliva and plasma.

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