Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-07-31
1999-11-23
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 71, 435 915, 4352402, 4351723, 536 241, 436 63, 436501, 935 6, 935 17, 935 36, 935 78, 935 77, C12Q 168, C12P 1934, G01N 3353, C07H 2104
Patent
active
059898100
ABSTRACT:
Activation of NF-AT-dependent transcription, including agents which interfere with the production, modification of the nuclear or cytoplasmic subunits, or the nuclear import of the cytoplasmic subunits. In particular, screening tests for novel immunosuppressants are provided based upon the ability of NF-AT to activate transcription.
REFERENCES:
Verwiej et al J. Biol Chem (1990) 265:15788-15795.
Sambrook et al, Molecular Cloning: A Laboratory Manual, 1989, Cold Spring Harbor Laboratory Press, NY, pp. 10.31-10.33.
Sawadogo et al, Cell (1985) 43:165-175.
Emmel et al Science (1989) 246:1617-1619
Shaw et al. Science (1988) 241:202-205.
Crabtree Gerald R.
Flanagan William M.
Board of Trustees of Leland Stanford Jr. University
Jones W. Gary
Myers Carla
LandOfFree
Screening methods for immunosuppressive agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Screening methods for immunosuppressive agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Screening methods for immunosuppressive agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1220097