Screening methods for cytokine inhibitors

Details Screening methods for cytokine inhibitors Screening methods for cytokine inhibitors

1998-06-15

1999-10-05

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

424 7805, A61K 31445

Patent

active

059624779

ABSTRACT:
The present invention provides a number of screening methods for evaluatiing compounds capable of suppressing cytokine production either in vitro or in vivo. The methods generally involve stimulating the production of a cytokine in a cell, exposing a portion of the cells to a putative cytokine modulating agent and determining subsequent levels of cytokine production in the cells. Additionally, the present invention provides certain compounds identified by this method.

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