Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Testing efficacy or toxicity of a compound or composition
Patent
1996-06-10
1999-06-01
Saunders, David
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Testing efficacy or toxicity of a compound or composition
435 6, 435 721, 435 8, 435 21, 435 29, 530399, A61K 4900, A61K 3822, C12Q 168, C12Q 102
Patent
active
059086092
ABSTRACT:
The present invention relates to drug screening assays, and diagnostic and therapeutic methods for the treatment of body weight disorders, such as obesity, anorexia and cachexia, utilizing the melanocortin 4-receptor (MC4-R) as the target for intervention. The invention also relates to compounds that modulate the activity or expression of the MC4-R, and the use of such compounds in the treatment of body weight disorders.
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Gu Wei
Huszar Dennis
Lee Frank
Millennium Pharmaceuticals Inc.
Saunders David
VanderVegt F. Pierre
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