Screening methods for compounds useful in the regulation of...

Details Screening methods for compounds useful in the regulation of... Screening methods for compounds useful in the regulation of...

2005-11-01

2005-11-01

Saucier, Sandra E. (Department: 1651)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Reexamination Certificate

active

06960430

ABSTRACT:
The present invention relates to drug screening assays and methods for the treatment of proliferative disorders associated with elevated levels of heat shock protein 72 (Hsp72) expression in a cell. The invention is based on the discovery that overexpression of full length Hsp72 protein, or the C-terminal protein binding domain of Hsp72, results in oncogenic transformation of cells.

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