Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2008-04-29
2008-04-29
Martinell, James (Department: 1634)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Reexamination Certificate
active
07365164
ABSTRACT:
Provided herein are a method for selecting a gene participating in the desired brewing character and compiling a database of the whole genome sequence of industrial yeast; identifying a gene participating in a brewing characteristic from the database; functional analysis of the gene; and a DNA array of the whole genome sequences of an industrial yeast. Also provided are a method for yeast breeding; a method of producing an alcoholic beverage with improved quality; and a screening method to identify genes that increase productivity and/or improve flavor in the production of an alcohol or an alcoholic beverage by (A) analyzing a whole industrial yeast genome sequence, (B) comparing the genome sequence with the genome sequence ofS. cerevisiae, (C) selecting a gene of the industrial yeast encoding having 70 to 97% identity to an amino acid sequence ofS. cerevisiae; and (D) analyzing the selected gene.
REFERENCES:
patent: 4885357 (1989-12-01), Larkins et al.
patent: 6326184 (2001-12-01), Gjermansen et al.
Avram et al., “SSU 1 Encodes a Plasma Membrane Protein with a Central Role in a Network of Proteins Conferring Sulfite Tolerance inSaccharomyces cerevisiae,” Journal of Bacteriology, 1997, vol. 179, No. 18, pp. 5971-5974, American Society of Microbiology, Washington, D.C.
Becker et al., “High-Efficiency Transformation of Yeast by Electroporation,”Methods in Enzymology, 1991, vol. 194, pp. 182-187, Academic Press, Inc., New York.
Blattner et al., “The Complete Genome Sequence ofEscherichia coliK-12,”Science, 1977, vol. 277, pp. 1453-1462, American Association for the Advancement of Science, Washington, D.C.
Carter et al., “Improved oligonucleotide site-directed mutagenesis using M13 vectors,”Nucleic Acids Research, 1985, vol. 13, No. 12, pp. 4431-4443, Oxford University Press, Oxford, England.
Cole et al., “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence,”Nature, 1998, vol. 393, pp. 537-544, Nature Publishing Group, London, England.
Gjermansen, C., “Construction of a Hybrid Brewing Strain of Saccharomyces Carlsbergensis by Mating of Meiotic Segregants,”Carlsberg Res. Commun., 1981, vol. 46, pp. 1-11, Copenhagen Valby, Denmark.
Goldstein et al., “Three New Dominant Drug Resistance Cassettes for Gene Disruption inSaccharomyces cerevisia,” Yeast, 1999, vol. 15, pp. 1541-1553, Wiley & Sons, Chichester, England and New York.
Goto-Yamamoto et al., “SSU1-R, a Sulphite Resistance Gene of Wine Yeast, is an Allele of SSU1 with a Different Upstream Sequence,” Journal of Fermentation of Bioengineering, 1988, vol. 86, No. 10, pp. 427-433.
Hansen et al., “Inactivation of MET 10 in brewer's yeast specifically increases SO2formation during beer production,”Nature Biotechnology, 1996, vol. 14, Nature America, New York. pp. 1587-1591.
Hansen et al., “Modification of biochemical pathways in industrial yeasts,” Journal of Biotechnology, 1996, pp. 1-12, vol. 49, Elsevier Science, Amsterdam, Holland.
Hinnen et al., “Transformation of yeast,”Proc. Natl. Acad. Sci. USA, 1978, vol. 75, No. 4, pp. 1929-1933, National Academy of Sciences, Washington, D.C.
Hussain et al., “Characterization of PDR4, aSaccharomyces cerevisiaegene that confers pleiotropic drug resistance in high-copy number,”Gene, 1991, vol. 101, pp. 149-152, Elsevier, Amsterdam, Holland.
Ito et al., “Transformation of Intact Yeast Cells Treated with Alkali Cations,”Journal of Bacteriology, 1983, vol. 153, No. 1, pp. 163-168, American Society for Microbiology, Washington, D.C.
Johannesen, “Saccharomyces pastorianusadenosine-5' -phosphosulfate kinase (MET14-CA) gene,” GenBank Database Online, 2002, Database Accession No. AY 017216, XP-002285924.
Johannesen et al., “Differential transcriptional regulation of sulfur assimilation gene homologues in theSaccharomyces carlsbergensisyeast species hybrid,” FEMS Yeast Research, 2002, pp. 315-322, vol. 1, No. 4, Elsevier Science B.V., Amsterdam, Holland.
Joubert et al., “Identification by mass spectrometry to two-dimensional gel electrophoresis-separated proteins extracted from lager brewing yeast,” Electrophoresis, vol. 22, 2001, pp. 2969-2982, Wiley-VCH, Weinheim, Germany.
Karin et al., “Primary structure and transcription of an amplified genetic locus: The CUP1 locus of yeast,”Proc. Natl. Acad. Sci. USA, 1984, vol. 81, pp. 337-341, National Academy of Sciences, Washington, D.C.
Korch et al., “A mechanism for sulfite production in beer and how to increase sulfite levels by recombinant genetics,”Yeast and Fermentation, pp. 201-208, 1991.
Kunkel, T., “Rapid and Efficient site-specific mutagenesis without phenotypic selection,”Proc. Natl. Acad. Sci. USA, 1985, vol. 82, pp. 488-492, National Academy of Sciences, Washington, D.C.
Lashkari et al., “Yeast microarrays for genome wide parallel genetic and gene expression analysis,” Proc. Natl. Acad. Sci. USA, 1997, pp. 13057-13062, vol. 94, National Academy of Sciences, Washington, D.C.
Makino et al., “Complete Nucleotide Sequences of 93-kb and 3.3-kb Plasmids of an EnterohemorrhagicEscherichia coliO157:H7 Derived from Sakai Outbreak,” DNA Research, 1998, vol. 5, pp. 1-9, Kazusa DNA Research Institute & Universal Academy Press, Tokyo, Japan.
Martini et al., “Deoxyribonucleic Acid Relatedness among Species of the GenusSaccharomycesSensu Stricto,”International Journal of Systematic Bacteriology, 1985, vol. 35, No. 4, pp. 508-511.
Matasuzaki,Saccharomyces bayanusMET14 gene for adenosine-5'-phosphosulfate 3'-phosphotransferase, 2000, Abstract, submitted to the EMBL/GenBank/DDBJ databases. AB 049836.
Olesen et al., “The Dynamics of theSaccharomyces carlsbergensisbrewing yeast transcriptome during a production-scale lager beer fermentation,”FEM Yeast Research, 2000, vol. 2, pp. 563-573, Elsevier Science, Amsterdam, Holland.
Park et al., “SSU1 mediates sulphite efflux inSaccharomyces cerevisiae,” Yeast, 2000, vol. 16, pp. 881-888, John Wiley & Sons, Chichester, England and New York.
Sanger, F., “Determination of Nucleotide Sequences in DNA,” Science, 1981, vol. 214, pp. 1205-1215, American Association for the Advancement of Science, Washington, D.C.
Sijen et al., Transcriptional and posttranscriptional gene silencing are mechanistically related,Current Biology, 2001, vol. 11, pp. 436-440, Current Biology, London, England.
Tamai et al., “Co-existence of Two Types of Chromosome in the Bottom Fermenting Yeast,Sacchaomyces cerevisiae,” Yeast, 1998, vol. 10, pp. 923-933, Wiley & Sons, Ltd., Chichester, England & New York.
Waterman, M., “Computer Analysis of Nucleic Acid Sequences,” Methods in Enzymology, 1988, vol. 164, pp. 765-793, Academic Press, New York.
Wells et al., “Cassette mutagenesis: an efficient method for generation of multiple mutations at defined sites,”Gene, 1985, vol. 34, pp. 315-323, Elsevier, Amsterdam, Holland.
Winzeler et al., “Genetic Diversity in Yeast Assessed with Whole-Genome Oligonucleotide Arrays,” Genetics, 2003, pp. 79-89, vol. 163, Bethesda, Maryland.
Wodicka et al., “Genome-wide edprssion monitoring inSaccharomyces cerevisiae,” Nature Biotechnology, 1997, pp. 1359-1367, vol. 15, Nature America, New York.
Ashikari Toshihiko
Fujimura Tomoko
Kodama Yukiko
Nakamura Norihisa
Nakao Yoshihiro
Drinker Biddle & Reath LLP
Martinell James
Suntory Limited
LandOfFree
Screening method for genes of brewing yeast does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Screening method for genes of brewing yeast, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Screening method for genes of brewing yeast will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2794743