Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1998-02-26
1998-12-29
McKelvey, Terry A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
G01N 33566
Patent
active
058540032
ABSTRACT:
The invention provides methods and compositions relating to a novel kinase, NIK, involved in NF.kappa.B activation. The polypeptides may be produced recombinantly from transformed host cells from the disclosed NIK encoding nucleic acids or purified from human cells. The invention provides isolated NIK hybridization probes and primers capable of specifically hybridizing with the disclosed NIK genes, NIK-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.
REFERENCES:
Malinin et al, Nature, vol. 385, pp. 540-544, Feb. 6, 1997.
Rothe Mike
Wu Lin
McKelvey Terry A.
Osman Richard Aron
Tularik Inc.
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