Screening method

Details Screening method Screening method

2007-10-09

2007-10-09

Ketter, James (Department: 1636)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S007100

Reexamination Certificate

active

10178912

ABSTRACT:
The invention relates to methods for the identification of novel receptors and/or novel ligands. The invention is based on the concept that parasites have developed a number of biologically active compounds in their saliva to cope with the defense mechanisms of the host organisms on which they feed and to manipulate the biological functions of host molecules to their advantage. These saliva compounds can be used to identify novel molecules within the host systems. Furthermore, these saliva compounds can be used to elucidate the functions of molecules whose existence is already known.

REFERENCES:
patent: 0 404 055 (1990-05-01), None
patent: 0404055 (1990-12-01), None
patent: 0404055 (1990-12-01), None
Wang et al. Immunglobulin G binding proteins in the ixodid ticks,Rhipicephalus appendiculatus, Amblyomma variegatumandIxodes hexagonusParsitology (1995), 111, 161-165.
Titus et al., FASEB Journal, 13:A954 (1999).
Wang et al., Parasitology, 111:161-165 (1995).
Wang et al., Parasitology, 109:525-530 (1994).

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