Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-08-28
2000-11-28
Graser, Jennifer
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 71, 435 732, 435 74, 435 18, 435 19, 435 24, 435 32, 435 691, 435 698, 4351721, 4351723, 435183, 435243, 536 243, 536 2432, C12Q 168
Patent
active
061533815
ABSTRACT:
Assays for the detection of .beta.-lactamase induction can be used to identify compounds that kill bacteria (i.e., bacteriocidal activity) or inhibit bacterial growth (i.e., bacteriostatic activity). The .beta.-lactamase can be encoded, for example, by a .beta.-lactamase gene carried by a bacterial host. The identified compounds can be use to treat bacterial infections in organisms such as mammals. The new methods can be used, for example, for high throughput screening of libraries of potential inhibitors.
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Graser Jennifer
Millennium Pharmaceuticals Inc.
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