Screening assays using nucleic acids encoding receptors for bomb

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 721, 435 691, 4352523, 43525411, 435325, 530350, C12Q 100, C07K 14705, C12N 1512

Patent

active

058144633

ABSTRACT:
Pure nucleic acids encoding novel receptors for bombesin-like peptides, the novel receptors themselves, and their antibodies. Also disclosed is a method of screening for a compound capable of interacting with any of these novel receptors.

REFERENCES:
Battey and Wada, "Two distinct receptor subtypes for mammalian bombesin-like peptides," TINS, 14:524-528, 1991.
Battey et al., Molecular cloning of the bombes in/gastrin-releasing peptide receptor from Swiss T3T cells PNAS, 88:395-399 (1991).
Fathi, et al., "BRS-3: A Novel Bombesin Receptor Subtype Selectively Expressed in Testis and Lung Carcinoma Cells," The Journal of Biological Chemistry, 268:5979-5984, 1993.
Giladi, et al., "Molecular Cloning and Characterization of Receptors for the Mammalian Bombesin-Like Peptides," Journal of Molecular Neuroscience, 4:41-54, 1993.
Giladi and Spindel, "Simple Luminometric Assay to Detect Phosphoinositol-Linked Receptor Expression in Xenopus Oocytes," BioTechniques, 10:744-747, 1991.
Gorbulev, et al., "Molecular cloning of a new bombesin receptor subtype expressed in uterus during pregnacy," Eur. J. Biochem, 208:405-410, 1992.
Julius, et al., "Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor," Science, 241:558-564, 1988.
Moody, T.W., et al., "Characterization of Receptors for Bombesin/Gastrin-Releasing Peptide in Human and Murine Cells," Methods Enzymol, 168:481-493, 1989.
Nagalla, et al., "Gastrin-releasing Peptide (GRP) Is Not Mammalian Bombesin," The Journal of Biological Chemistry, 267:6916-6922, 1992.
Spindel, et al., "Cloning and Functional Characterization of a Complementary DNA Encoding the Murine Fibroblast Bombesin . . . , " Molecular Endocrinology, 4:1956-1963, 1990.
Sandberg, et al., "Calcium mobilization by angiotensin II and neurotransmitter receptors expressed in Xenopus Laevis oocytes," FEBS Lett., 241:177-180, 1988.
Shirakawa, et al., "Interaction between stimuli and their antagonists on frog esophageal peptic glands" Am. J. Physiol. 249(6 pt 1):668-673 (1985).
Von Schrenck, et al., "Neuromedian B receptor in esophagus: evidence for subtypes of bombesin receptors," Bombesin Receptor Subtypes, 256:G-747-G758, 1989.
Wada, et al., "cDNA Cloning, Characterization, and Brain Region-Specific Expression of a Neuromedian-B-Preferring Bombesin Receptor," Neuron, 6:421-430, 1991.
Wada, et al., "Comparison of Gene Expression for Two Distinct Bombesin Receptor Subtypes in Postnatal Rat Central Nervous System," Molecular and Cellular Neurosciences, 3:446-460, 1992.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Screening assays using nucleic acids encoding receptors for bomb does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Screening assays using nucleic acids encoding receptors for bomb, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Screening assays using nucleic acids encoding receptors for bomb will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-685266

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.