Screening assays for compounds that cause apoptosis

Details Screening assays for compounds that cause apoptosis Screening assays for compounds that cause apoptosis

2003-08-04

2008-03-04

Gupta, Anish (Department: 1654)

Chemistry: analytical and immunological testing

Peptide, protein or amino acid

C436S501000

Reexamination Certificate

active

07338807

ABSTRACT:
This invention relates to methods of screening for compounds capable of inducing apoptosis in certain tumor cells. The invention also relates to compounds identified by such methods. In addition, the invention relates to methods for the in vitro diagnosis ofXeroderma pigmentosumand compounds useful in these methods.

REFERENCES:
patent: 5484710 (1996-01-01), Reed et al.
patent: 5604113 (1997-02-01), White et al.
Proceedings of the American Association for Cancer Research, vol. 35, Mar. 1994, p. 585.
Molecular and Cellular Biology, Hua Xiao, et al. “Binding of Basal Transcription Factor TFIIH to the Acidic Activation Domains of VP16 and p53,” vol. 14, No. 10, Oct. 1994, pp. 7013-7024.
The EMBO Journal, L. Schaeffer, V. Moncollin, et al., “The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor,” vol. 13, No. 10, pp. 2388-2392, 1994.
Nature, Imperial Cancer Research Fund, Clare Hall Laboratories,“Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells,” vol. 349, Jan. 31, 1991, pp. 429-431.
The New England Journal of Medicine, C. Harris, M. Hollstein, “Review Articles,” Oct. 28, 1993, pp. 1318-1327.
Proc. Natl. Acad. Sci. USA, “Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3,” Xin Wei Wang, et al., vol. 91, pp. 2230-2234, Mar. 1994 Medical Sciences.
SCIENCE, “DNA Repair Helicase: A Component of BTF2 (TFIIH) Basic Transcription Factor,” Laurent Schaeffer, et al., vol. 260, Apr. 2, 1993, pp. 58-63.
The Journal of Biological Chemistry, “The DNA-dependent ATPase Activity Associated with the Class II Basic Transcription Factor BTF2/TFIIH,” vol. 269, No. 13, Issue of April, pp. 9826-9832, 1994.

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