Screening assay utilizing the PTH receptor

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S325000, C435S455000, C530S350000, C536S023500

Reexamination Certificate

active

09869565

ABSTRACT:
The invention provides a novel PTH receptor polypeptide, rΔNt, characterized by a deletion of the extracellular amino-terminus, ligand binding domain of the receptor. Additionally disclosed are nucleic acid molecules encoding the receptor. The receptor has a minimal domain for ligand binding and is useful in screening assays designed for the identification of agonists and antagonists of PTH receptor activity.

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