Screening assay for inhibitors of human cytochrome P-450

Details Screening assay for inhibitors of human cytochrome P-450 Screening assay for inhibitors of human cytochrome P-450

2006-06-06

2006-06-06

Saucier, Sandra E. (Department: 1651)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Reexamination Certificate

active

07056654

ABSTRACT:
Fluorescein derivative as a substrate for cytochrome P450 enzymes.

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Miller, et al., “Flow cytometric techniques for measurement of cytochrome P-450 activity in viable cells.”, (1990), Methods in Cell Biology, 33, pp. 71-79.
White, et al., “Characteristics of Rat Hepatocytes Sorted by Fluorescence-Activated Flow Cytometry Effects of Mixed Function Oxidase Inducers”, (1989), Biochemical Pharmacology, vol. 38, No. 10, p. 1639-1646.
White, et al., “Fluorescence-Activated Sorting of Rat Hapatocytes Based on Their Mixed Function Oxidase Activities Towards Diethoxyfluorescein”, Biochemical Journal, vol. 247, No. 1, pp. 23-28, (1987).

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