Multicellular living organisms and unmodified parts thereof and – Method of using a transgenic nonhuman animal in an in vivo...
Reexamination Certificate
2004-01-28
2008-10-14
Ketter, James (Department: 1636)
Multicellular living organisms and unmodified parts thereof and
Method of using a transgenic nonhuman animal in an in vivo...
C800S013000, C435S320100, C435S006120, C536S024100
Reexamination Certificate
active
07435868
ABSTRACT:
The invention relates to the identification and use of the DAF-2/IR responsive sod-3 promoter. TransgenicC. eleganscontaining sod-3 reporter gene constructs are described which are useful for, among other things, the identification of genes or compounds capable of modulating the DAF-2/IR-akt pathway. Conditions are disclosed that increase or decrease the reporter activity, demonstrating the presence of either activators or inhibitors of the DAF-2/IR pathway.
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Hoppe Edmund
Rothblatt Jonathan
Schauerte Heike
Siebers Ulrike
Ketter James
Sanofi-Aventis Deutschland GmbH
Szezepanik Ann Marie
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