Screening antibodies for capacity to deliver toxin to target cel

Details Screening antibodies for capacity to deliver toxin to target cel Screening antibodies for capacity to deliver toxin to target cel

1985-09-30

1987-08-25

Marantz, Sidney

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is a biological cell or cell fragment

424 85, 435 7, 435 29, 436547, 436548, 530389, G01N 3353, A61K 3100

Patent

active

046893113

ABSTRACT:
Treatment and screening materials and methods (as for cancer) are provided in which there is provided between a toxin and an anticancer antibody an intermediate antibody with an affinity for either the toxin or the anticancer antibody.

REFERENCES:
patent: 4340535 (1982-07-01), Voisin
patent: 4401764 (1983-08-01), Smith
patent: 4468382 (1984-08-01), Bacha
patent: 4543211 (1985-09-01), Kato
Chemical Abstracts, 103:109913w (1985).
Murphy, J. R. et al., J. Clin. Microbiol., 7(1), 91-96 (1978).

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