Screening and therapeutic methods relating to neurogenesis

Details Screening and therapeutic methods relating to neurogenesis Screening and therapeutic methods relating to neurogenesis

2008-01-29

2008-01-29

Romeo, David (Department: 1647)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of regulating cell metabolism or physiology

C435S325000, C435S354000, C435S365000, C435S368000, C512S012000

Reexamination Certificate

active

07323334

ABSTRACT:
The invention provides methods of identifying compounds that modulate neurogenesis. The methods involve providing a compound that modulates prokineticin receptor signaling; contacting a neural stem or progenitor cell with the compound; and determining the ability of the compound to modulate neurogenesis. The invention also provides methods for modulating neurogenesis. The methods involve contacting a neural stem or progenitor cell with an effective amount of a compound that modulates prokineticin receptor signaling. Such methods are useful for both ex vivo or in vivo therapeutic applications where neural regeneration is desirable.

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GenBank Accession No. AF487278, Jun. 9, 2002.
GenBank Accession No. AF487279, Jun. 9, 2002.
GenBank Accession No. AF487280, Jun. 9, 2002.

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